Understanding the interaction mechanisms between cell hosts and bacterial agents is a key point to fight infections. To better understand these phenomena, models of polarized epithelial cell infections have been developed and have been proven to be very effective and predictive of bacterial interactions with the mucosal barrier in vivo.
SMALTIS is therefore equipped with a cell culture laboratory dedicated to this activity and proposes to carry out for you the infection of epithelial cells and to evaluate the adhesion, the invasion and the cytotoxicity of your strains and in parallel the cellular response.
Bacterial Adhesion & Invasion
Cellular Infection & Response